BDBM50509342 CHEMBL4438430

SMILES COc1cc(ccc1NS(C)(=O)=O)C(=O)N1CCc2c(C1)c(=O)oc1c(C)c(ccc21)N1CCN(C)CC1

InChI Key InChIKey=JYXFPWJRSZGEBC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50509342   

LigandPNGBDBM50509342(CHEMBL4438430)
Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant MTHFD2 (unknown origin) using THF as substrate incubated for 30 mins in presence of NADMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetC-1-tetrahydrofolate synthase, cytoplasmic(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50509342(CHEMBL4438430)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant MTHFD1 (unknown origin) using THF as substrate incubated for 30 mins in presence of NADMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed