BDBM50508994 CHEMBL4589118

SMILES Cc1c(OCc2ccccc2)cccc1N1CCN(CCCCCCNc2c3CCCCc3nc3CCCCc23)CC1

InChI Key InChIKey=BOTHFECTSJELMD-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50508994   

TargetAcetylcholinesterase(Human)
Julius Maximilian University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50508994(CHEMBL4589118)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50508994(CHEMBL4589118)
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Julius Maximilian University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50508994(CHEMBL4589118)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]-LSD from recombinant human 5HT6 receptor expressed in CHOK1 cells measured after 60 mins by microbeta scintillation counting met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed