BDBM50508934 CHEMBL4463817

SMILES [H][C@@]12CC[C@@]3(C)c4[nH]c5ccccc5c4C[C@@]([H])(NC1(C)C)[C@@]3([H])C2

InChI Key InChIKey=QYBCOSRUKXCALD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50508934   

TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
American University of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50508934(CHEMBL4463817)
Affinity DataIC50: 400nMAssay Description:Antagonist activity at human AChR alpha3beta4 transfected in human HEK293 cells assessed as decrease in epibatidine-induced calcium influx incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
American University of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50508934(CHEMBL4463817)
Affinity DataIC50: 3.40E+3nMAssay Description:Antagonist activity at human AChR alpha4beta2 transfected in human HEK293 cells assessed as decrease in epibatidine-induced calcium influx incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
American University of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50508934(CHEMBL4463817)
Affinity DataIC50: 2.70E+4nMAssay Description:Antagonist activity at human AChR alpha7 transfected in rat GH3 cells assessed as decrease in epibatidine-induced calcium influx incubated for 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed