BDBM50508911 CHEMBL4452888

SMILES CCCOC(=O)c1cc(ccc1Cl)-c1ccc(\C=C2\NC(=S)NC2=O)o1

InChI Key InChIKey=ROQWMUVYMUOSQS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50508911   

TargetGlycogen synthase kinase-3 alpha(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50508911(CHEMBL4452888)
Affinity DataIC50: 159nMAssay Description:Inhibition of human GSK-3alpha S449A mutant (2 to end residues) using phospho GS2 peptide as substrate after 40 mins in presence of [gamma-33ATP] by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50508911(CHEMBL4452888)
Affinity DataIC50: 405nMAssay Description:Inhibition of human GSK-3beta H350L mutant (2 to end residues) at 10 uM using phospho GS2 peptide as substrate after 40 mins by [gamma-33ATP] radiome...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed