BDBM50508883 CHEMBL4536515

SMILES Cc1c(C)c(ccc1-c1ccc(\C=C2\SC(=N)NC2=O)o1)[N+]([O-])=O

InChI Key InChIKey=VMHDKSJEGBWITL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50508883   

TargetGlycogen synthase kinase-3 alpha(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50508883(CHEMBL4536515)
Affinity DataIC50: 227nMAssay Description:Inhibition of human GSK-3alpha S449A mutant (2 to end residues) using phospho GS2 peptide as substrate after 40 mins in presence of [gamma-33ATP] by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50508883(CHEMBL4536515)
Affinity DataIC50: 571nMAssay Description:Inhibition of human GSK-3beta H350L mutant (2 to end residues) at 10 uM using phospho GS2 peptide as substrate after 40 mins by [gamma-33ATP] radiome...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed