BDBM50508778 CHEMBL4450262

SMILES CC1(C)OC(=O)Nc2cccc(Oc3cc(Cl)cc(c3)C#N)c12

InChI Key InChIKey=SDQJBFCZZXWMLO-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50508778   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
Stellenbosch University

Curated by ChEMBL
LigandPNGBDBM50508778(CHEMBL4450262)
Affinity DataIC50: 2.76E+3nMAssay Description:Inhibition of HIV1 reverse transcriptase G190A mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Stellenbosch University

Curated by ChEMBL
LigandPNGBDBM50508778(CHEMBL4450262)
Affinity DataIC50: 798nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Stellenbosch University

Curated by ChEMBL
LigandPNGBDBM50508778(CHEMBL4450262)
Affinity DataIC50: 28nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Stellenbosch University

Curated by ChEMBL
LigandPNGBDBM50508778(CHEMBL4450262)
Affinity DataIC50: 630nMAssay Description:Inhibition of HIV1 reverse transcriptase V106M mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Stellenbosch University

Curated by ChEMBL
LigandPNGBDBM50508778(CHEMBL4450262)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of HIV1 reverse transcriptase Y188H mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Stellenbosch University

Curated by ChEMBL
LigandPNGBDBM50508778(CHEMBL4450262)
Affinity DataIC50: 21nMAssay Description:Inhibition of wild-type HIV1 reverse transcriptase in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infection ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Stellenbosch University

Curated by ChEMBL
LigandPNGBDBM50508778(CHEMBL4450262)
Affinity DataIC50: 7nMAssay Description:Inhibition of HIV1 reverse transcriptase Y188C mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Stellenbosch University

Curated by ChEMBL
LigandPNGBDBM50508778(CHEMBL4450262)
Affinity DataIC50: 894nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed