BDBM50508776 CHEMBL4470380

SMILES Cn1c2c(Oc3cc(Cl)cc(c3)C#N)cccc2[nH]c1=O

InChI Key InChIKey=HOBUPBKXAJVBGV-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50508776   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
Stellenbosch University

Curated by ChEMBL
LigandPNGBDBM50508776(CHEMBL4470380)
Affinity DataIC50: 236nMAssay Description:Inhibition of HIV1 reverse transcriptase Y188C mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Stellenbosch University

Curated by ChEMBL
LigandPNGBDBM50508776(CHEMBL4470380)
Affinity DataIC50: 29nMAssay Description:Inhibition of wild-type HIV1 reverse transcriptase in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infection ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Stellenbosch University

Curated by ChEMBL
LigandPNGBDBM50508776(CHEMBL4470380)
Affinity DataIC50: 126nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Stellenbosch University

Curated by ChEMBL
LigandPNGBDBM50508776(CHEMBL4470380)
Affinity DataIC50: 55nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Stellenbosch University

Curated by ChEMBL
LigandPNGBDBM50508776(CHEMBL4470380)
Affinity DataIC50: 74nMAssay Description:Inhibition of HIV1 reverse transcriptase Y188H mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Stellenbosch University

Curated by ChEMBL
LigandPNGBDBM50508776(CHEMBL4470380)
Affinity DataIC50: 107nMAssay Description:Inhibition of HIV1 reverse transcriptase G190A mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Stellenbosch University

Curated by ChEMBL
LigandPNGBDBM50508776(CHEMBL4470380)
Affinity DataIC50: 494nMAssay Description:Inhibition of HIV1 reverse transcriptase V106M mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed