BDBM50508775 CHEMBL4457636

SMILES Nc1nc(=O)n(cc1Cl)-c1cccc(c1)-c1ccccc1

InChI Key InChIKey=QMGYGOOYCNTEQO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50508775   

TargetMethylcytosine dioxygenase TET1(Human)
Bates College

Curated by ChEMBL
LigandPNGBDBM50508775(CHEMBL4457636)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged TET1 (1418 to 2136 residues) expressed in baculovirus infected sf9 cells assessed as reduction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetMethylcytosine dioxygenase TET2(Human)
Bates College

Curated by ChEMBL
LigandPNGBDBM50508775(CHEMBL4457636)
Affinity DataIC50: 7.30E+4nMAssay Description:Inhibition of recombinant human C-terminal His/N-terminal FLAG-tagged TET2 (1129 to 2002 residues) expressed in baculovirus infected sf9 cells assess...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetMethylcytosine dioxygenase TET1(Human)
Bates College

Curated by ChEMBL
LigandPNGBDBM50508775(CHEMBL4457636)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of TET1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMethylcytosine dioxygenase TET2(Human)
Bates College

Curated by ChEMBL
LigandPNGBDBM50508775(CHEMBL4457636)
Affinity DataIC50: 7.30E+4nMAssay Description:Inhibition of TET2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed