BDBM50508765 CHEMBL4455234::US11091474, Example 3

SMILES COCC(Cc1c[nH]c2ccccc12)NC(=O)c1cnc(s1)N1CCN(C)CC1

InChI Key InChIKey=VUCDCRBMCWPOAL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50508765   

TargetAlpha-synuclein(Human)
Drexel University

Curated by ChEMBL
LigandPNGBDBM50508765(CHEMBL4455234 | US11091474, Example 3)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of alpha-synuclein (unknown origin) self-aggregation by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAlpha-synuclein(Human)
Drexel University

Curated by ChEMBL
LigandPNGBDBM50508765(CHEMBL4455234 | US11091474, Example 3)
Affinity DataIC50: 4.60E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
Go to US Patent