BDBM50508746 CHEMBL4526092

SMILES Cc1cc(cc(C)n1)N1CC[C@@]2(CCN(Cc3ccc4nccnc4c3)C2)C1

InChI Key InChIKey=KJUZVOMMESDTBC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50508746   

TargetProtein O-GlcNAcase(Human)
Drexel University

Curated by ChEMBL
LigandPNGBDBM50508746(CHEMBL4526092)
Affinity DataIC50: 224nMAssay Description:Inhibition of recombinant human full length OGA using FM-GlcNAc as substrate preincubated for 60 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Drexel University

Curated by ChEMBL
LigandPNGBDBM50508746(CHEMBL4526092)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of OGA in HEK293 cells assessed as increase in O-GlcNAcylated protein level by Hoechst staining based microscopic methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed