BDBM50508661 CHEMBL4524830

SMILES Cn1cc(C2CCCCC2)c2cc(F)c(cc12)C(=O)NS(=O)(=O)C1CC1

InChI Key InChIKey=ACCWQRXHODRNFI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50508661   

TargetCytochrome P450(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50508661(CHEMBL4524830)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP450More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50508661(CHEMBL4524830)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human Nav1.5 at -50 mV holding potential by cell-based IonWorks barracuda automated electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50508661(CHEMBL4524830)
Affinity DataIC50: 30nMAssay Description:Inhibition of human Nav1.7 at -60 mV holding potential by cell-based IonWorks barracuda automated electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50508661(CHEMBL4524830)
Affinity DataIC50: 14nMAssay Description:Inhibition of human Nav1.7 at -60 mV holding potential by cell-based manual patch clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed