BDBM50508399 CHEMBL4441142

SMILES Fc1ccc2[nH]cc(C3=C(C(=O)NC3=O)c3cc(ccc3C(F)(F)F)N3CCN(CC3)C(=O)C=C)c2c1

InChI Key InChIKey=VGPLCKCUFQEEGH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50508399   

TargetTyrosine-protein kinase JAK3(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50508399(CHEMBL4441142)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human N-terminal His-tagged JAK3 (795 to 1124 residues) expressed in baculovirus expression system in presence of 6 uM ATP by HTRF assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50508399(CHEMBL4441142)
Affinity DataIC50: 895nMAssay Description:Inhibition of human N-terminal His-tagged JAK3 (795 to 1124 residues) expressed in baculovirus expression system in presence of 1 mM ATP by HTRF assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed