BDBM50508389 CHEMBL4444559

SMILES FC(F)(F)c1ccc(cc1C1=C(C(=O)NC1=O)c1c[nH]c2ccccc12)N1CCC[C@H](C1)NC(=O)C=C

InChI Key InChIKey=STCBITIZMNQJLU-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50508389   

TargetTyrosine-protein kinase JAK3(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50508389(CHEMBL4444559)
Affinity DataIC50: 21nMAssay Description:Inhibition of human N-terminal His-tagged JAK3 (795 to 1124 residues) expressed in baculovirus expression system in presence of 6 uM ATP by HTRF assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50508389(CHEMBL4444559)
Affinity DataKi:  201nMAssay Description:Inhibition of human N-terminal His-tagged JAK3 (795 to 1124 residues) expressed in baculovirus expression system in presence of 6 uM ATP by HTRF assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50508389(CHEMBL4444559)
Affinity DataIC50: 3.69E+3nMAssay Description:Inhibition of human N-terminal His-tagged JAK3 (795 to 1124 residues) expressed in baculovirus expression system in presence of 1 mM ATP by HTRF assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed