BDBM50507814 CHEMBL4464784
SMILES COc1cccc(c1)C(C)(C)NC[C@@H](O)[C@H](Cc1ccccc1)NC(=O)c1cccc(c1)C(=O)NCC(C)(C)C
InChI Key InChIKey=GJKQZFJOCTXOHB-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50507814
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human cathepsin D using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate preincubated for 30 mins followed by substrate additi...More data for this Ligand-Target Pair
TargetPlasmepsin I(malaria parasite P. falciparum)
Latvian Institute of Organic Synthesis
Curated by ChEMBL
Latvian Institute of Organic Synthesis
Curated by ChEMBL
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 1 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate preincubated for 30 mins followed by...More data for this Ligand-Target Pair
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate preincubated for 30 mins followed by...More data for this Ligand-Target Pair
TargetPlasmepsin IV [1-448](malaria parasite P. falciparum)
Latvian Institute of Organic Synthesis
Curated by ChEMBL
Latvian Institute of Organic Synthesis
Curated by ChEMBL
Affinity DataIC50: 76nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 4 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate preincubated for 30 mins followed by...More data for this Ligand-Target Pair