BDBM50507802 CHEMBL4542566

SMILES COc1cccc(c1)C(C)(C)NC[C@@H](O)[C@H](Cc1ccccc1)NC(=O)c1cc(cc(c1)C(=O)NCCN(C)C)N1CCCCC1

InChI Key InChIKey=FXMLQRDALQEISW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50507802   

TargetPlasmepsin IV [1-448](malaria parasite P. falciparum)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50507802(CHEMBL4542566)
Affinity DataIC50: 360nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 4 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate preincubated for 30 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetCathepsin D(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50507802(CHEMBL4542566)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human cathepsin D using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate preincubated for 30 mins followed by substrate additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed