BDBM50507737 CHEMBL4514989

SMILES Cn1nc(O)c(C(O)=O)c1CNc1ccccc1

InChI Key InChIKey=YXURSAIUJSPFDO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50507737   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50507737(CHEMBL4514989)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant N-terminal His6-tagged DHODH (159-569 residues) expressed in Escherichia coli BL21(DE3) using DHO as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50507737(CHEMBL4514989)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged DHODH (31 to 395 residues) expressed in Escherichia coli BL21(DE3) using DHO as substrate prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed