BDBM50507420 CHEMBL4529447

SMILES OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2ccc(F)cc2F)c1=O

InChI Key InChIKey=DWOPGWHMZNCHQB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50507420   

TargetProlyl hydroxylase EGLN3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50507420(CHEMBL4529447)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of recombinant human HIF-PHD3 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50507420(CHEMBL4529447)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of recombinant human HIF-PHD2 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProlyl hydroxylase EGLN2(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50507420(CHEMBL4529447)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of recombinant human HIF-PHD1 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed