BDBM50507415 CHEMBL4451025

SMILES OC(=O)CNC(=O)c1c(O)c2cc(OC(F)(F)F)cc3OC(Cn(c23)c1=O)c1ccc(cc1)C#N

InChI Key InChIKey=WKLDLAIFXJRTMG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50507415   

TargetProlyl hydroxylase EGLN3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50507415(CHEMBL4451025)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of recombinant human HIF-PHD3 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProlyl hydroxylase EGLN2(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50507415(CHEMBL4451025)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant human HIF-PHD1 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50507415(CHEMBL4451025)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human HIF-PHD2 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed