BDBM50507130 CHEMBL4452983

SMILES Clc1ccc2c(NC(=O)[C@@H](Cc3ccccn3)N(Cc3ccc(cc3)C(=O)c3c[nH]c4cccnc34)C2=O)c1

InChI Key InChIKey=AOGRUGIWISIXLO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50507130   

TargetToxin B(Peptoclostridium difficile)
Venenum Biodesign

Curated by ChEMBL
LigandPNGBDBM50507130(CHEMBL4452983)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of Clostridium difficile toxin B transfected in CHO cells assessed as reduction in caspase 3/7 activation pre-incubated for 1 hr before Tc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetToxin A(Peptoclostridium difficile)
Venenum Biodesign

Curated by ChEMBL
LigandPNGBDBM50507130(CHEMBL4452983)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of Clostridium difficile toxin A transfected in CHO cells assessed as reduction in caspase 3/7 activation pre-incubated for 1 hr before Tc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetToxin B(Peptoclostridium difficile)
Venenum Biodesign

Curated by ChEMBL
LigandPNGBDBM50507130(CHEMBL4452983)
Affinity DataIC50: 2nMAssay Description:Inhibition of C-terminal 6-His tagged recombinant Clostridium difficile toxin B glucosyltransferase domain assessed as reduction in UDP-glucose hydro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed