BDBM50507018 CHEMBL4582715

SMILES [O-][N+](=O)c1ccc(cc1)C(=O)Nc1nc(nc2ccccc12)-c1ccccc1

InChI Key InChIKey=XBJOUPFIBJIIBB-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50507018   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50507018(CHEMBL4582715)Copy SMILESCopy InChI

Affinity DataIC50: 93nMAssay Description:Inhibition of GFP-fused human ABCG2 expressed in MDCK2 cells assessed as Hoechst 33342 accumulation preincubated for 30 mins followed by Hoechst 3334...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/19/2021
Entry Details Article
Copy Entry DOIPubMed
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TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50507018(CHEMBL4582715)Copy SMILESCopy InChI

Affinity DataIC50: 77nMAssay Description:Inhibition of GFP-fused human ABCG2 expressed in MDCK2 cells assessed as potentiation of mitoxantrone-induced cytotoxicity after 72 hrs by MTT assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/19/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL