BDBM50506912 CHEMBL235641

SMILES O=C1Nc2ccc3ncsc3c2\C1=C\c1c[nH]cn1

InChI Key InChIKey=VFBGXTUGODTSPK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50506912   

TargetSerine/threonine-protein kinase Nek7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50506912(CHEMBL235641)
Affinity DataIC50: 7.28E+3nMAssay Description:Inhibition of human NEK7 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Nek6(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50506912(CHEMBL235641)
Affinity DataIC50: 5.98E+4nMAssay Description:Inhibition of human NEK6 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50506912(CHEMBL235641)
Affinity DataIC50: 144nMAssay Description:Inhibition of human MLK3 by ATP-competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50506912(CHEMBL235641)
Affinity DataIC50: 61nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed