BDBM50506853 CHEMBL3959384

SMILES c1cc(cc(c1)S(=O)(=O)Oc2ccc(cc2)C(=O)O)NC(=O)Nc3ccc(cc3N)Cl

InChI Key InChIKey=HGNQXSWLGVYPCQ-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50506853   

TargetGenome polyprotein(ZIKV)
Cnrs Umr7258

Curated by ChEMBL
LigandPNGBDBM50506853(CHEMBL3959384)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of ZIKV 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGenome polyprotein(WNV)
Cnrs Umr7258

Curated by ChEMBL
LigandPNGBDBM50506853(CHEMBL3959384)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of WNV 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Cnrs Umr7258

Curated by ChEMBL
LigandPNGBDBM50506853(CHEMBL3959384)
Affinity DataIC50: 3.69E+5nMAssay Description:Inhibition of DENV3 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed