BDBM50506851 CHEMBL4475329

SMILES OC(=O)c1cccc(CNS(=O)(=O)c2cccc(NC(=O)Nc3ccc(cc3[N+]([O-])=O)C(F)(F)F)c2)c1

InChI Key InChIKey=LRXFVKURDWTGJM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50506851   

TargetGenome polyprotein(ZIKV)
Cnrs Umr7258

Curated by ChEMBL
LigandPNGBDBM50506851(CHEMBL4475329)
Affinity DataIC50: 1.36E+5nMAssay Description:Inhibition of ZIKV 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Cnrs Umr7258

Curated by ChEMBL
LigandPNGBDBM50506851(CHEMBL4475329)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of DENV3 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed