BDBM50506820 CHEMBL4513282

SMILES COC(=O)c1ccccc1NC(=O)CCN1CCc2ccccc2C1

InChI Key InChIKey=JFYMYKHSDMIJPH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50506820   

LigandPNGBDBM50506820(CHEMBL4513282)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues) /human N-terminal His-tagged MEP50 (2 to end residues) expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50506820(CHEMBL4513282)
Affinity DataIC50: 3.41E+4nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as enzymatic activity by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed