BDBM50506690 CHEMBL4541986

SMILES Cc1cc(Nc2ccc3nc(C)cc(N)c3c2)nc(Nc2ccc3nc(C)cc(N)c3c2)n1

InChI Key InChIKey=CNRRJWSSDCTLTQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50506690   

TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
Zhejiang Ocean University

Curated by ChEMBL
LigandPNGBDBM50506690(CHEMBL4541986)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of DOT1L (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
Zhejiang Ocean University

Curated by ChEMBL
LigandPNGBDBM50506690(CHEMBL4541986)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of DOT1L (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
Zhejiang Ocean University

Curated by ChEMBL
LigandPNGBDBM50506690(CHEMBL4541986)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human DOT1L (1 to 416 residues) expressed in Escherichia coli (DE3) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed