BDBM50506659 CHEMBL4467327

SMILES O=C(CCN1CCN(Cc2ccccc2)CC1)Nc1nc(cs1)-c1ccccc1

InChI Key InChIKey=DTIQJBUDKQVBLT-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50506659   

TargetMyeloid differentiation primary response protein MyD88(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50506659(CHEMBL4467327)
Affinity DataKd:  1.80E+5nMAssay Description:Binding affinity to recombinant human MyD88 TIR domain (157 to 296 residues) expressed in Escherichia coli BL21(DE3) by surface plasmon resonance ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50506659(CHEMBL4467327)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of recombinant human MMP-2 using QF24 as substrate incubated for 3 hrs by spectrofluorometer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50506659(CHEMBL4467327)
Affinity DataIC50: 1.19E+4nMAssay Description:Inhibition of recombinant human MMP-8 using QF24 as substrate incubated for 3 hrs by spectrofluorometer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed