BDBM50506637 CHEMBL4476226

SMILES CN(c1cccc2CN(Cc12)c1nc(Nc2ccc(cc2)N2CCN(CC2)C(C)=O)ncc1C(F)(F)F)S(C)(=O)=O

InChI Key InChIKey=OIXHMSMLJCOUJT-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50506637   

TargetFocal adhesion kinase 1(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50506637(CHEMBL4476226)
Affinity DataIC50: 11nMAssay Description:Inhibition of human FAK using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50506637(CHEMBL4476226)
Affinity DataIC50: 3nMAssay Description:Inhibition of human AuroraA using [H-LRRASLG] as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50506637(CHEMBL4476226)
Affinity DataIC50: 25nMAssay Description:Inhibition of human MER using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50506637(CHEMBL4476226)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human FLT3 using EAIYAAPFAKKK as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50506637(CHEMBL4476226)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of human SYK using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor TYRO3(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50506637(CHEMBL4476226)
Affinity DataIC50: 50nMAssay Description:Inhibition of human TYRO3 using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50506637(CHEMBL4476226)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of N-terminal His-tagged recombinant human AXL (473 to end amino acids) expressed by baculovirus in Sf9 cells using axltide substrate and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50506637(CHEMBL4476226)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human AXL using EAIYAAPFAKKK as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50506637(CHEMBL4476226)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of human PLK1 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed