BDBM50506479 CHEMBL4454572

SMILES Clc1ccc2[nH]c(=O)c(CNc3ccc([nH]c3=O)C#N)cc2c1

InChI Key InChIKey=BJRNSMBACDBVMT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50506479   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50506479(CHEMBL4454572)
Affinity DataIC50: 65nMAssay Description:Inhibition of recombinant human Myc-DDK-tagged IDH1 R132H mutant using alpha-ketoglutarate as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed