BDBM50506400 CHEMBL4458212

SMILES FC(F)(F)c1ccc(\C=C\C2CCN(CC#C)CC2)cc1

InChI Key InChIKey=MDTRBZGINQEXRZ-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50506400   

TargetAmine oxidase [flavin-containing] B(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50506400(CHEMBL4458212)
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human microsomal MAOB expressed in baculovirus infected BTI insect cells using p-tyramine as substrate preincubated for 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50506400(CHEMBL4458212)
Affinity DataKi:  1.25E+3nMAssay Description:Reversible inhibition of recombinant human MAOB expressed in Pichia pastoris using varying levels of kynuramine as substrate measured after 5 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50506400(CHEMBL4458212)
Affinity DataKi:  1.73E+4nMAssay Description:Irreversible inhibition of recombinant human MAOB expressed in Pichia pastoris using varying levels of kynuramine as substrate measured after 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed