BDBM50506380 CHEMBL4587968::US20240122941, Compound 15

SMILES Cn1cc(cn1)-c1ccc2c(CC[C@]22NC(=O)N(CC(=O)N3Cc4cc(F)ccc4OC[C@H]3C(F)(F)F)C2=O)c1

InChI Key InChIKey=VDEZYUOBIXKTHI-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50506380   

TargetN-alpha-acetyltransferase 40(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50506380(CHEMBL4587968 | US20240122941, Compound 15)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NatD (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT7(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50506380(CHEMBL4587968 | US20240122941, Compound 15)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of KAT7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50506380(CHEMBL4587968 | US20240122941, Compound 15)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2B(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50506380(CHEMBL4587968 | US20240122941, Compound 15)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PCAF (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2A(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50506380(CHEMBL4587968 | US20240122941, Compound 15)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of GCN5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT8(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50506380(CHEMBL4587968 | US20240122941, Compound 15)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of MOF (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50506380(CHEMBL4587968 | US20240122941, Compound 15)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of p300 (unknown origin) using histone H3 (1 to 21 residues) as substrate preincubated for 15 mins followed by substrate and [3H]acetyl-Co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase type B catalytic subunit(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50506380(CHEMBL4587968 | US20240122941, Compound 15)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of HAT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50506380(CHEMBL4587968 | US20240122941, Compound 15)
Affinity DataIC50: 48nMAssay Description:SensoLyte HAT (p300) Assay Kit (ANASPEC, AS-72172) was used to assess the HAT activity inhibiting capability of a HAT inhibitor. Specifically, 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
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