BDBM50506251 CHEMBL4437023

SMILES CCn1nc(C)cc1C(=O)Nc1nc2cc(ccc2n1CCCNC(=O)OCc1ccccc1)C(N)=O

InChI Key InChIKey=IJSHVJXGHLYOSD-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50506251   

TargetInterferon regulatory factor 3(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50506251(CHEMBL4437023)
Affinity DataEC50: >1.00E+5nMAssay Description:Induction of IRF3 pathway in STING knockout human THP1 cells measured after 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50506251(CHEMBL4437023)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at STING in human THP1 cells assessed as stimulation of IRF3 pathway measured after 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed