BDBM50506083 CHEMBL4466314

SMILES [H][C@@]12CC[C@@]([H])(C1)C(C2)Nc1c(Nc2cccc(C(=O)N3CCCC3)c2O)c(=O)c1=O

InChI Key InChIKey=ZFEXFHOZIDYWSO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50506083   

TargetC-X-C chemokine receptor type 2(Human)
Hangzhou Institute of Innovative Medicine

Curated by ChEMBL
LigandPNGBDBM50506083(CHEMBL4466314)
Affinity DataIC50: 48nMAssay Description:Antagonist activity at CXCR2 (unknown origin) stably expressed in HEK293 cells co-expressing Galpha16 assessed as reduction in IL-8-induced intracell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Hangzhou Institute of Innovative Medicine

Curated by ChEMBL
LigandPNGBDBM50506083(CHEMBL4466314)
Affinity DataIC50: 2.90E+3nMAssay Description:Antagonist activity at CXCR1 (unknown origin) stably expressed in HEK293 cells co-expressing Galpha16 assessed as reduction in IL-8-induced intracell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed