BDBM50506011 CHEMBL4436698

SMILES N[C@@H](CCN(CCCc1cccc(c1)C(N)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(O)=O

InChI Key InChIKey=VSETVFOQAVXGIV-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50506011   

TargetNicotinamide N-methyltransferase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50506011(CHEMBL4436698)
Affinity DataIC50: 83nMAssay Description:Inhibition of recombinant NNMT (unknown origin) assessed as reduction in MNA concentration incubated for 10 mins measured after 30 mins by LC-MS/MS-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetNicotinamide N-methyltransferase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50506011(CHEMBL4436698)
Affinity DataKi:  43nMAssay Description:Inhibition of full-length human N-terminal TEV cleavage site NNMT (1 to 270 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL cells us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed