BDBM50505854 CHEMBL4458109

SMILES OC(=O)c1ccc(\C=C2/SC(=S)N(Cc3cccc(c3)C(F)(F)F)C2=S)cc1

InChI Key InChIKey=PASWUUGFZJSQDJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50505854   

TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50505854(CHEMBL4458109)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse bone marrow derived macrophages incubated for 30 mins by immunoblotting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed