BDBM50505848 CHEMBL4443648

SMILES CCn1c(nc2cc(C)ccc12)-c1ccccc1

InChI Key InChIKey=LAPXJMHYUYXOQN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50505848   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50505848(CHEMBL4443648)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed