BDBM50505770 CHEMBL4446073

SMILES OC(=O)\C=C1\CC(=O)N1

InChI Key InChIKey=MOUMOHZFKYZERP-UHFFFAOYSA-N

Data  3 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50505770   

TargetIntegrin alpha-V/beta-3(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50505770(CHEMBL4446073)
Affinity DataEC50:  76nMAssay Description:Agonist activity at alphaVbeta3 integrin receptor in human SK-MEL-24 cells assessed as increase in fibronectin-induced cell adhesion pre-incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50505770(CHEMBL4446073)
Affinity DataEC50:  255nMAssay Description:Agonist activity at alpha4beta1 integrin receptor in human Jurkat E6.1 cells assessed as increase in VCAM1-induced cell adhesion pre-incubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50505770(CHEMBL4446073)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to alpha5beta1 integrin receptor (unknown origin) incubated fro 30 mins by competitive solid-phase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50505770(CHEMBL4446073)
Affinity DataIC50: 294nMAssay Description:Binding affinity to alpha4beta1 integrin receptor (unknown origin) incubated for 1 hr by scintillation proximity binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50505770(CHEMBL4446073)
Affinity DataIC50: 29nMAssay Description:Binding affinity to alphaVbeta3 integrin receptor (unknown origin) incubated fro 30 mins by competitive solid-phase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50505770(CHEMBL4446073)
Affinity DataEC50:  154nMAssay Description:Agonist activity at alphaVbeta3 integrin receptor in human Saos-2 cells assessed as increase in fibronectin-induced cell adhesion pre-incubated for 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed