BDBM50505768 CHEMBL4439225

SMILES CS(=O)(=O)c1cc(Br)cc(c1)-c1nnc(o1)-c1ccc(cc1)C(=O)N[C@@H](Cn1ccnc1)c1ccc(cc1Cl)-c1ccc(F)cc1

InChI Key InChIKey=GWNWIEYNTYTQJX-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50505768   

TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50505768(CHEMBL4439225)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of recombinant full length human CYP51 expressed in Escherichia coli incubated for 1 hr using [3H] lanosterol as substrate by HPLC analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50505768(CHEMBL4439225)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant full length human CYP51 expressed in Escherichia coli incubated for 1 min using [3H] lanosterol as substrate by HPLC analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50505768(CHEMBL4439225)
Affinity DataKd:  130nMAssay Description:Binding affinity to recombinant full length human CYP51 expressed in Escherichia coli incubated for 30 sec using [3H] labelled substrate by HPLC anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed