BDBM50505648 CHEMBL4562149

SMILES C[C@H](NS(=O)(=O)c1ccc(OCC(F)=C/CN)cc1)c1ccccc1

InChI Key InChIKey=ZVFVOMFIUGHFMF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50505648   

TargetLysyl oxidase homolog 2(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505648(CHEMBL4562149)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetProtein-lysine 6-oxidase(Bovine)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505648(CHEMBL4562149)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAmine oxidase [copper-containing] 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505648(CHEMBL4562149)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human SSAO using benzylamine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed