BDBM50505635 CHEMBL4472333

SMILES CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(CC(F)=CCN)c2ccccc12

InChI Key InChIKey=FFWWSSGIANHKJO-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50505635   

TargetD-amino-acid oxidase(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505635(CHEMBL4472333)
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of recombinant human DAO using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505635(CHEMBL4472333)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of recombinant human MAOB expressed in baculovirus infected in BTI cells using benzylamine as substrate preincubated with enzyme for 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505635(CHEMBL4472333)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAmine oxidase [copper-containing] 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505635(CHEMBL4472333)
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibition of recombinant human SSAO using benzylamine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetProtein-lysine 6-oxidase(Bovine)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505635(CHEMBL4472333)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505635(CHEMBL4472333)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of recombinant human MAOA expressed in baculovirus infected in BTI cells using tyramine as substrate preincubated with enzyme for 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed