BDBM50505634 CHEMBL4569453

SMILES CN(C)S(=O)(=O)c1ccc(OCc2cn(CC(F)=CCN)nn2)cc1

InChI Key InChIKey=VAFPYUKSDDVHFR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50505634   

TargetLysyl oxidase homolog 2(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505634(CHEMBL4569453)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetProtein-lysine 6-oxidase(Bovine)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505634(CHEMBL4569453)
Affinity DataIC50: 794nMAssay Description:Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505634(CHEMBL4569453)
Affinity DataIC50: 126nMAssay Description:Inhibition of recombinant human MAOB expressed in baculovirus infected in BTI cells using benzylamine as substrate preincubated with enzyme for 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505634(CHEMBL4569453)
Affinity DataIC50: 316nMAssay Description:Inhibition of recombinant human DAO using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAmine oxidase [copper-containing] 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505634(CHEMBL4569453)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of recombinant human SSAO using benzylamine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed