BDBM50505628 CHEMBL4449512
SMILES Fc1c(Cl)cccc1[C@H]1[C@@H](NC2(CCCCC2)[C@@]11C(=O)Nc2cc(Cl)ccc12)C(=O)NCCCCCc1cccc2C(=O)N(Cc12)C1CCC(=O)NC1=O
InChI Key InChIKey=BANRYGZZIMCKNA-UHFFFAOYSA-N
Data 17 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 17 hits for monomerid = 50505628
Affinity DataIC50: 623nMAssay Description:Binding affinity to cereblon in human MDA-MB-231 cells assessed as reduction in cell growth inhibition measured after 4 days in presence of 10 uM of ...More data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Displacement of PMDM6-F fluorescent probe from human recombinant His-tagged MDM2 (1 to 118 residues) after 15 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.37E+3nMAssay Description:Binding affinity to cereblon in human MDA-MB-231 cells assessed as reduction in cell growth inhibition measured after 4 days in presence of 30 uM of ...More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Binding affinity to cereblon in human RV4:11/IRMI-2 cells harboring p53 hotspot mutation Y236H/R249G assessed as reduction in cell growth inhibition ...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Binding affinity to cereblon in human MDA-MB-231 cells assessed as cell growth inhibition measured after 4 daysMore data for this Ligand-Target Pair
Affinity DataIC50: 2.14E+3nMAssay Description:Binding affinity to cereblon in human MDA-MB-231 cells assessed as reduction in cell growth inhibition measured after 4 days in presence of 100 uM of...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Binding affinity to cereblon in human MDA-MB-468 cells assessed as cell growth inhibition measured after 4 daysMore data for this Ligand-Target Pair
Affinity DataIC50: 2.07E+3nMAssay Description:Binding affinity to cereblon in human MDA-MB-468 cells assessed as reduction in cell growth inhibition measured after 4 days in presence of 100 uM le...More data for this Ligand-Target Pair
Affinity DataIC50: 964nMAssay Description:Binding affinity to cereblon in human MDA-MB-468 cells assessed as reduction in cell growth inhibition measured after 4 days in presence of 30 uM len...More data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Binding affinity to cereblon in human RV4:11/IRMI-2 cells harboring p53 hotspot mutation Y236H/R249G assessed as cell growth inhibition measured afte...More data for this Ligand-Target Pair
Affinity DataIC50: 982nMAssay Description:Binding affinity to cereblon in human RV4:11/IRMI-2 cells harboring p53 hotspot mutation Y236H/R249G assessed as reduction in cell growth inhibition ...More data for this Ligand-Target Pair
Affinity DataIC50: 168nMAssay Description:Binding affinity to cereblon in human RV4:11/IRMI-2 cells harboring p53 hotspot mutation Y236H/R249G assessed as reduction in cell growth inhibition ...More data for this Ligand-Target Pair
Affinity DataIC50: 496nMAssay Description:Binding affinity to cereblon in human RV4:11 cells expressing wild type p53 assessed as reduction in cell growth inhibition measured after 4 days in ...More data for this Ligand-Target Pair
Affinity DataIC50: 211nMAssay Description:Binding affinity to cereblon in human RV4:11 cells expressing wild type p53 assessed as reduction in cell growth inhibition measured after 4 days in ...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Binding affinity to cereblon in human RV4:11 cells expressing wild type p53 assessed as cell growth inhibition measured after 4 daysMore data for this Ligand-Target Pair
Affinity DataIC50: 419nMAssay Description:Binding affinity to cereblon in human MDA-MB-468 cells assessed as reduction in cell growth inhibition measured after 4 days in presence of 10 uM len...More data for this Ligand-Target Pair
Affinity DataIC50: 96nMAssay Description:Binding affinity to cereblon in human RV4:11 cells expressing wild type p53 assessed as reduction in cell growth inhibition measured after 4 days in ...More data for this Ligand-Target Pair