BDBM50505616 CHEMBL3590172

SMILES CO[C@H]1O[C@H](CNS(=O)(=O)c2c(C)cc(C)cc2C)[C@@H](O)[C@H](O)[C@@H]1O

InChI Key InChIKey=RVGBPVTVQRZPOK-UHFFFAOYSA-N

Data  3 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50505616   

TargetFucose-binding lectin PA-IIL(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50505616(CHEMBL3590172)
Affinity DataIC50: 1.86E+3nMAssay Description:Competitive inhibition of N-(fluorescein-5-yl)-N'-(alpha-L-fucopyranosyl ethylen)-thiocarbamide binding to Pseudomonas aeruginosa PA14 LecB after 8 t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFucose-binding lectin PA-IIL(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50505616(CHEMBL3590172)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa PAO1 LecB after 6 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFucose-binding lectin PA-IIL(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50505616(CHEMBL3590172)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant Pseudomonas aeruginosa LecB expressed in Escherichia coli BL21 (DE3) expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetFucose-binding lectin PA-IIL(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50505616(CHEMBL3590172)
Affinity DataKd:  3.30E+3nMAssay Description:Binding affinity to recombinant Pseudomonas aeruginosa LecB expressed in Escherichia coli BL21 (DE3) expression system assessed as dissociation const...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetPA-I galactophilic lectin(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Helmholtz Institute For Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50505616(CHEMBL3590172)
Affinity DataKd:  3.30E+3nMAssay Description:Binding affinity to Pseudomonas aeruginosa PAO1 LecA assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed