BDBM50505567 CHEMBL4457500

SMILES COC1=CC(=O)N([C@H]1C)C(=O)\C=C\[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)OC(=O)[C@H](C(C)C)N(C)C

InChI Key InChIKey=XFUISEXCEYJHFX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50505567   

TargetProcathepsin L(Human)
The University of Jordan

Curated by ChEMBL
LigandPNGBDBM50505567(CHEMBL4457500)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
The University of Jordan

Curated by ChEMBL
LigandPNGBDBM50505567(CHEMBL4457500)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed