BDBM50505547 CHEMBL4453088

SMILES OC[C@]1(O)CN(C[C@@H]1Oc1ccc(C#N)c(F)c1)S(=O)(=O)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=VXWNRMAUQHKNHT-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50505547   

TargetTransient receptor potential cation channel subfamily V member 4(Human)
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50505547(CHEMBL4453088)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:Antagonist activity at BacMam virus expressing human TRPV4 transduced in BHK/AC9 or HEK MSR2 cells assessed as inhibition of GSK634775-induced Ca2+ f...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/18/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL