BDBM50505507 CHEMBL4461910

SMILES COc1cc(OC)cc(Sc2ccc(cc2)C(C)N(C)c2ncc3c(N)nc(N)nc3n2)c1

InChI Key InChIKey=CJJJMEFPIHPFRP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50505507   

TargetNAD-dependent protein deacetylase(Blood fluke)
University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50505507(CHEMBL4461910)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of recombinant Schistosoma mansoni sirtuin 2 (21 to 322 residues) expressed in Escherichia coli BL21(DE3) cells using ZMAL as substrate af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50505507(CHEMBL4461910)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of N-terminal His6 tagged human sirtuin 2 (25 to 389 residues) assessed as inhibition of substrate demyristoylation using (Z)-(Myr)-Lys-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed