BDBM50505357 CHEMBL4579464

SMILES Brc1ccc(Sc2ccc3C(NCCC(=O)NCCOCCOCCNc4cccc5C(=O)N(C6CCC(=O)NC6=O)C(=O)c45)=C(C#N)C(=O)c4cccc2c34)cc1

InChI Key InChIKey=SXKROLVLGUDXTB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50505357   

LigandPNGBDBM50505357(CHEMBL4579464)
Affinity DataIC50: 2.29E+3nMAssay Description:Inhibition of biotinylated Bim peptide (81 to 106 residues) binding to His-tagged human Mcl-1 expressed in Escherichia coli BL21 (DE3) cells preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50505357(CHEMBL4579464)
Affinity DataIC50: 2.24E+3nMAssay Description:Inhibition of biotinylated Bim peptide (81 to 106 residues) binding to His-tagged human Bcl-2 expressed in Escherichia coli BL21 (DE3) cells preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed