BDBM50505119 CHEMBL4449793

SMILES Clc1ccc(CN2CCN(CC2)C(=O)C(=O)Nc2ccc3[nH]c(=O)oc3c2)cc1

InChI Key InChIKey=JTJNSDDAXJHYNG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50505119   

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50505119(CHEMBL4449793)
Affinity DataIC50: 501nMAssay Description:Displacement of [3H]-ifenprodil from NR2B receptor in rat brain cerebral cortex membranes incubated for 120 mins by liquid scintillation counting met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50505119(CHEMBL4449793)
Affinity DataIC50: 63nMAssay Description:Antagonist activity at mouse NR2B receptor expressed in HEK293 cells co-expressing NR1 subunit assessed as reduction in glutamic acid/glycine-induced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed