BDBM50505045 CHEMBL4470699

SMILES [H][C@]12[C@H](C)O[C@H](C)CN1c1c(CC22C(=O)NC(=O)NC2=O)cc2c(noc2c1F)N1C[C@H](CC)SC1=O

InChI Key InChIKey=PENBFHXGXXEUQX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50505045   

TargetDNA topoisomerase 2-alpha(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50505045(CHEMBL4470699)
Affinity DataIC50: 1.28E+5nMAssay Description:Inhibition of human topoisomerase-2alpha using catenated DNA as substrate after 30 mins by ethidium bromide-based gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50505045(CHEMBL4470699)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling activity using relaxed pHOT-1 DNA as substrate after 60 mins by ethidium bromide-based ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed