BDBM50504453 CHEMBL1984399

SMILES [O-][N+](=O)\C=C\c1cccc(F)c1

InChI Key InChIKey=NOXNBNYWEWJUTM-UHFFFAOYSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50504453   

TargetFructose-1,6-bisphosphatase 1(Human)
International Cooperation Base of Pesticide and Green Synthesis (Hubei)

Curated by ChEMBL
LigandPNGBDBM50504453(CHEMBL1984399)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human FBPase D127A mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green dye b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
International Cooperation Base of Pesticide and Green Synthesis (Hubei)

Curated by ChEMBL
LigandPNGBDBM50504453(CHEMBL1984399)
Affinity DataIC50: 890nMAssay Description:Inhibition of human FBPase C179S mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green dye b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
International Cooperation Base of Pesticide and Green Synthesis (Hubei)

Curated by ChEMBL
LigandPNGBDBM50504453(CHEMBL1984399)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human FBPase Y258A mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green dye b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
International Cooperation Base of Pesticide and Green Synthesis (Hubei)

Curated by ChEMBL
LigandPNGBDBM50504453(CHEMBL1984399)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of human FBPase R254A mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green dye b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
International Cooperation Base of Pesticide and Green Synthesis (Hubei)

Curated by ChEMBL
LigandPNGBDBM50504453(CHEMBL1984399)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human FBPase R243A mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green dye b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
International Cooperation Base of Pesticide and Green Synthesis (Hubei)

Curated by ChEMBL
LigandPNGBDBM50504453(CHEMBL1984399)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human FBPase N125A mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green dye b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
International Cooperation Base of Pesticide and Green Synthesis (Hubei)

Curated by ChEMBL
LigandPNGBDBM50504453(CHEMBL1984399)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human FBPase S124A mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green dye b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
International Cooperation Base of Pesticide and Green Synthesis (Hubei)

Curated by ChEMBL
LigandPNGBDBM50504453(CHEMBL1984399)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human FBPase C281S mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green dye b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
International Cooperation Base of Pesticide and Green Synthesis (Hubei)

Curated by ChEMBL
LigandPNGBDBM50504453(CHEMBL1984399)
Affinity DataIC50: 3.50E+5nMAssay Description:Inhibition of human FBPase C128S mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green dye b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
International Cooperation Base of Pesticide and Green Synthesis (Hubei)

Curated by ChEMBL
LigandPNGBDBM50504453(CHEMBL1984399)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human FBPase C116S mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green dye b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
International Cooperation Base of Pesticide and Green Synthesis (Hubei)

Curated by ChEMBL
LigandPNGBDBM50504453(CHEMBL1984399)
Affinity DataIC50: 620nMAssay Description:Inhibition of human FBPase C92S mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green dye ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
International Cooperation Base of Pesticide and Green Synthesis (Hubei)

Curated by ChEMBL
LigandPNGBDBM50504453(CHEMBL1984399)
Affinity DataIC50: 920nMAssay Description:Inhibition of human FBPase C183S mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green dye b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
International Cooperation Base of Pesticide and Green Synthesis (Hubei)

Curated by ChEMBL
LigandPNGBDBM50504453(CHEMBL1984399)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human FBPase C38S mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green dye ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
International Cooperation Base of Pesticide and Green Synthesis (Hubei)

Curated by ChEMBL
LigandPNGBDBM50504453(CHEMBL1984399)
Affinity DataIC50: 320nMAssay Description:Inhibition of human FBPase expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green dye based spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
International Cooperation Base of Pesticide and Green Synthesis (Hubei)

Curated by ChEMBL
LigandPNGBDBM50504453(CHEMBL1984399)
Affinity DataIC50: 320nMAssay Description:Inhibition of human wild type FBPase expressed in Escherichia coli BL12 (DE3) by malachite green methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed