BDBM50504439 CHEMBL4515160

SMILES Fc1ccc2[nH]cc(C3CC(=O)N(CCCCN4CCC(CC4)c4c[nH]c5ccc(F)cc45)C3=O)c2c1

InChI Key InChIKey=XKIVNUFBPASSIA-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50504439   

Target5-hydroxytryptamine receptor 1A(Human)
Medical University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50504439(CHEMBL4515160)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in CHO-K1 cell membranes incubated for 60 mins by microbeta scintillation counting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Medical University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50504439(CHEMBL4515160)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Medical University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50504439(CHEMBL4515160)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]-imipramine from human serotonin transporter expressed in HEK293 cells membranes incubated for 30 mins by microbeta scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Medical University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50504439(CHEMBL4515160)
Affinity DataKi:  301nMAssay Description:Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK293 cells incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Medical University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50504439(CHEMBL4515160)
Affinity DataKi:  1.16E+3nMAssay Description:Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cells incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Medical University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50504439(CHEMBL4515160)
Affinity DataKi:  1.94E+3nMAssay Description:Displacement of [3H]-Ketanserin from human 5-HT2A receptor expressed in rat cortex tissue incubated for 30 mins by liquid scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed